Topic #6: Platform Technologies
Historically, development of protein therapeutics relied on a customized approach for each new molecule. Early efforts focused on establishment of a fixed process that delivered the required quality. Unfortunately, this approach limited application of continuous improvement and incorporation of new technologies to enable improvements in safety and efficacy.
In an effort to address this, platform technologies, in which prior knowledge was collected and leveraged for new molecules, were identified. Platform molecules can then proceed through development using standardized, manufacturing processes. In contrast , a customized approach is created for non-platform molecules, for which more techniques and conditions have to be evaluated.
Our experts weigh in on how they are applying platform technologies, best practices, and the benefits they have experienced.